TETRAMER | retinoids-driven Neuronal cell differentiation

First gene induction observation
T1-BJ
T3-BJ
T6-BJ
T16-BJ
T24-BJ
Edges
Activation

 The list of selected genes below can be visualized in geneMANIA

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GeneCards NameBJELM_BJ BJEL_rel_BJ BubbleRouter_CellularComponents BubbleRouter_GenMAPP_Pathways SUID T1_BJ T3_BJ T6_BJ T8_BJ T16_BJ T24_BJ canonicalName first_DE_index first_DE_name id name selected shared_name yield
NFATC2 -0.09821557998657227 0.10588566958904266 [cytoplasmnucleus] [B_Cell_Receptor_NetPath_12T-Cell-Receptor_NetPath_11] 105 0.49302366375923157 1.5852227210998535 1.4397506713867188 1.5557886362075806 0.056747667491436005 0.5100006461143494 NFATC2 1 T3-BJ 105 NFATC2 false NFATC2 58.24175824175825
HSF2 0.5806737542152405 0.4943639934062958 [cytoplasmnucleus] [] 88 0.4661810100078583 0.5883499979972839 0.6414170265197754 0.5830100178718567 0.9821670055389404 1.1709409952163696 HSF2 5 T24-BJ 88 HSF2 false HSF2 52.52747252747253
LRPPRC 1.0320149660110474 0.4680466651916504 [cytoplasmintracellularmitochondrionnucleus] [TNF-alpha-NF-kB_NetPath_9] 78 0.7828400135040283 0.8401700258255005 0.8206300139427185 0.7162500023841858 1.0142600536346436 0.7618700265884399 LRPPRC 4 T16-BJ 78 LRPPRC false LRPPRC 63.73626373626373
FOSB 0.0504085011780262 -0.13751299679279327 [nucleus] [TGF-beta-Receptor_NetPath_7] 94 0.31649601459503174 -0.0331990011036396 -0.23967300355434418 -0.05452600121498108 -0.18006600439548492 1.1055279970169067 FOSB 5 T24-BJ 94 FOSB false FOSB 68.57142857142857
JUNB -0.9997422695159912 -0.8193293213844299 [intracellularnucleus] [Oxidative_StressTGF-beta-Receptor_NetPath_7] 95 1.0351439714431763 -0.14734399318695068 -1.4487179517745972 -1.3581479787826538 -1.28547203540802 -0.4071449935436249 JUNB 0 T1-BJ 95 JUNB false JUNB 68.35164835164835
RFC1 0.9569829702377319 0.8449363112449646 [intracellularnucleus] [DNA_replication_Reactome] 80 0.7241129875183105 0.8641629815101624 0.8257730007171631 0.6911529898643494 1.096222996711731 0.9408929944038391 RFC1 4 T16-BJ 80 RFC1 false RFC1 61.31868131868132
PRKDC 1.4024430513381958 0.9570580124855042 [nucleus] [Cell_Cycle_KEGGCell_cycle_KEGGFas_Pathway_and_Stress_Induction_of_HSP_Regulation_Biocarta] 79 1.3000680208206177 1.3506180047988892 1.4802279472351074 1.3587980270385742 1.598557949066162 1.0495280027389526 PRKDC 0 T1-BJ 79 PRKDC false PRKDC 55.824175824175825
GPBP1 0.7124441862106323 0.899433970451355 [nucleus] [] 122 0.8360806703567505 0.8518646955490112 0.943036675453186 0.6603506803512573 1.0606366395950317 1.085296630859375 GPBP1 4 T16-BJ 122 GPBP1 false GPBP1 31.648351648351646
DNAJC2 1.1065834760665894 0.7173506617546082 [nucleus] [] 115 0.8113279938697815 0.9107400178909302 0.8854910135269165 0.7610200047492981 0.8972489833831787 1.0200070142745972 DNAJC2 5 T24-BJ 115 DNAJC2 false DNAJC2 56.043956043956044
REL 0.3271739184856415 0.35793599486351013 [cytoplasmintracellularnucleus] [B_Cell_Receptor_NetPath_12TNF-alpha-NF-kB_NetPath_9] 124 0.5792686939239502 2.4145727157592773 0.8124926686286926 0.35124266147613525 0.5734876394271851 0.28489765524864197 REL 1 T3-BJ 124 REL false REL 67.25274725274726
MSC 0.10853641480207443 -0.42467001080513 [nucleus] [Id_NetPath_5NetPath_5] 123 0.07218966633081436 1.2085856199264526 0.4367126524448395 0.3051856756210327 1.9064797163009644 1.6818727254867554 MSC 1 T3-BJ 123 MSC false MSC 33.18681318681318
MXD1 -0.28647175431251526 -0.1466200053691864 [intracellularnucleus] [] 85 -0.30079999566078186 -0.6378600001335144 -0.6578670144081116 -0.6372789740562439 0.4536449909210205 1.063770055770874 MXD1 5 T24-BJ 85 MXD1 false MXD1 56.48351648351648
ARNTL -0.2406190037727356 0.32285434007644653 [nucleus] [Circadian_Exercise] 126 0.569491982460022 0.5219410061836243 0.8451820015907288 0.8957880139350891 1.1773970127105713 1.2868690490722656 ARNTL 4 T16-BJ 126 ARNTL false ARNTL 58.681318681318686
ZBTB11 0.528415858745575 0.448086678981781 [intracellularnucleus] [] 121 0.4590943455696106 0.4683303236961365 0.4101773202419281 0.21764633059501648 0.569062352180481 1.032313346862793 ZBTB11 5 T24-BJ 121 ZBTB11 false ZBTB11 41.318681318681314
HIVEP3 0.29874059557914734 0.5168293118476868 [intracellularnucleus] [Delta-Notch_NetPath_3] 119 0.6459593176841736 1.5576093196868896 1.4001383781433105 1.2786003351211548 0.07467932999134064 0.8968283534049988 HIVEP3 1 T3-BJ 119 HIVEP3 false HIVEP3 46.15384615384615
CEBPG 0.1434759944677353 0.09474000334739685 [nucleus] [] 97 0.1408730000257492 -0.04350699856877327 0.025519000366330147 -0.05907899886369705 1.3036240339279175 1.1384299993515015 CEBPG 4 T16-BJ 97 CEBPG false CEBPG 54.505494505494504
ANKRD1 -0.4958236813545227 0.6246776580810547 [cytoplasmintracellularnucleus] [Hypertrophy_model] 96 2.571986436843872 2.4207842350006104 2.910877227783203 3.16837739944458 2.14436936378479 4.021637439727783 ANKRD1 0 T1-BJ 96 ANKRD1 false ANKRD1 65.93406593406593
BHLHE40 -0.10796158015727997 -0.1428246647119522 [] [] 75 1.2373557090759277 0.878935694694519 -0.12118833512067795 -0.007933332584798336 0.02397266775369644 0.0443226657807827 BHLHE40 0 T1-BJ 75 BHLHE40 false BHLHE40 66.59340659340658
BACH1 0.3988094925880432 0.4114103317260742 [nucleus] [] 120 1.0378799438476562 0.9872819781303406 1.1492979526519775 1.2115010023117065 0.9699869751930237 1.2674429416656494 BACH1 0 T1-BJ 120 BACH1 false BACH1 51.208791208791204
EGR1 -0.9100306034088135 0.03170200064778328 [intracellularnucleus] [Insulin_SignalingOvarian_Infertility_Genes] 81 1.57517671585083 -1.8815993070602417 -2.9242982864379883 -1.3753583431243896 -2.1851143836975098 -1.0211453437805176 EGR1 0 T1-BJ 81 EGR1 false EGR1 63.51648351648351
JUN 0.5432630181312561 0.830036997795105 [intracellularnucleus] [Androgen-Receptor_NetPath_2ApoptosisB_Cell_Receptor_NetPath_12Delta-Notch_NetPath_3EGFR1_NetPath_4ESC_Pluripotency_PathwaysFas_Pathway_and_Stress_Induction_of_HSP_Regulation_BiocartaFocal_adhesion_KEGGIL-5_NetPath_17IL-6_NetPath_18Insulin_SignalingMAPK_CascadeMAPK_signaling_pathway_KEGGMAPK_signaling_pathway_KEGGSignaling_of_Hepatocyte_Growth_Factor_Receptor_BiocartaSmooth_muscle_contractionT-Cell-Receptor_NetPath_11TGF-beta-Receptor_NetPath_7TGF_Beta_Signaling_PathwayWnt_NetPath_8Wnt_SignalingWnt_signaling] 99 1.6478979587554932 1.1595380306243896 0.43007799983024597 0.5770059823989868 -0.3171299993991852 1.061627984046936 JUN 0 T1-BJ 99 JUN false JUN 65.05494505494505
NPAS2 -0.8562725782394409 -0.8128373622894287 [intracellularnucleus] [] 106 -0.718488335609436 -0.46758833527565 -0.09661433100700378 -0.048692334443330765 1.013939619064331 0.48852965235710144 NPAS2 4 T16-BJ 106 NPAS2 false NPAS2 57.36263736263736
SUPT3H 0.91698157787323 0.760142982006073 [intracellularnucleus] [] 91 0.6722763180732727 0.8252783417701721 0.7739943265914917 0.664517343044281 1.2771813869476318 0.8078473210334778 SUPT3H 4 T16-BJ 91 SUPT3H false SUPT3H 62.417582417582416
KLF6 0.13674816489219666 0.5478363037109375 [cytoplasmintracellularnucleus] [Adipogenesis] 125 1.0182446241378784 0.8245776891708374 0.7408066391944885 0.7264866828918457 0.17544667422771454 0.5723816752433777 KLF6 0 T1-BJ 125 KLF6 false KLF6 65.27472527472527
ETS1 0.45537516474723816 0.6229343414306641 [nucleus] [IL-2_NetPath_14IL-4_NetPath_16TGF-beta-Receptor_NetPath_7] 112 0.6927876472473145 1.3402376174926758 1.2543376684188843 1.1315876245498657 0.763447642326355 0.9876276850700378 ETS1 1 T3-BJ 112 ETS1 false ETS1 45.27472527472528
GZF1 0.3658636808395386 0.5186323523521423 [intracellularnucleus] [] 118 0.7770896553993225 0.4359036684036255 0.7074286937713623 0.6480506658554077 1.187943696975708 1.4038887023925781 GZF1 4 T16-BJ 118 GZF1 false GZF1 59.56043956043956
NFIL3 -0.6476204991340637 -0.09855866432189941 [nucleus] [] 108 0.11625900119543076 0.18986600637435913 0.04433400183916092 -0.0381149984896183 1.3851879835128784 1.0361720323562622 NFIL3 4 T16-BJ 108 NFIL3 false NFIL3 71.42857142857143
HNRNPAB 0.7582675218582153 0.7450699806213379 [] [] 86 1.1811000108718872 1.159309983253479 0.9511200189590454 0.9503499865531921 0.7674800157546997 0.6296200156211853 HNRNPAB 0 T1-BJ 86 HNRNPAB false HNRNPAB 62.637362637362635
RELB 0.45163342356681824 0.45871567726135254 [intracellularnucleus] [TNF-alpha-NF-kB_NetPath_9] 89 0.537330687046051 1.2250746488571167 1.0637946128845215 0.8795326948165894 1.016824722290039 1.399479627609253 RELB 1 T3-BJ 89 RELB false RELB 61.53846153846154
MYC -0.22420300543308258 0.7090659737586975 [intracellularnucleus] [ApoptosisCell_Cycle-G1_to_S_control_ReactomeEGFR1_NetPath_4ESC_Pluripotency_PathwaysG1_to_S_cell_cycle_ReactomeMAPK_signaling_pathway_KEGGMAPK_signaling_pathway_KEGGTGF-beta-Receptor_NetPath_7Wnt_SignalingWnt_signalingp38_MAPK_signaling_pathway] 107 1.5875359773635864 0.7157160043716431 0.9642459750175476 1.090656042098999 1.5372459888458252 2.043466091156006 MYC 0 T1-BJ 107 MYC false MYC 64.83516483516483
ZNF410 0.22182725369930267 0.5237406492233276 [intracellularnucleus] [] 98 0.5384209752082825 0.7522799968719482 0.702455997467041 0.5918539762496948 1.1005569696426392 1.056488037109375 ZNF410 4 T16-BJ 98 ZNF410 false ZNF410 36.043956043956044
DDIT3 -0.039362832903862 -0.2722196578979492 [nucleus] [AdipogenesisMAPK_signaling_pathway_KEGGMAPK_signaling_pathway_KEGGp38_MAPK_signaling_pathway] 109 -0.9458873271942139 -1.4596682786941528 -0.4080193340778351 -0.9845003485679626 3.1581246852874756 2.7653746604919434 DDIT3 1 T3-BJ 109 DDIT3 false DDIT3 41.53846153846154
FOS -0.5544296503067017 -0.6437756419181824 [intracellularnucleus] [EGFR1_NetPath_4ESC_Pluripotency_PathwaysIL-6_NetPath_18Insulin_SignalingMAPK_signaling_pathway_KEGGMAPK_signaling_pathway_KEGGOxidative_StressSignaling_of_Hepatocyte_Growth_Factor_Receptor_BiocartaSmooth_muscle_contractionT-Cell-Receptor_NetPath_11TGF-beta-Receptor_NetPath_7TGF_Beta_Signaling_Pathway] 93 0.410807341337204 -0.6556696891784668 -0.8826436400413513 -0.6715106964111328 -0.6190646886825562 1.6632143259048462 FOS 5 T24-BJ 93 FOS false FOS 71.20879120879121
TAF1A 0.8977080583572388 0.949794352054596 [intracellularnucleus] [] 77 0.6697213053703308 0.922722339630127 1.1131473779678345 0.7770633101463318 1.3905843496322632 1.4285132884979248 TAF1A 2 T6-BJ 77 TAF1A false TAF1A 38.901098901098905
SNAPC1 0.39165931940078735 0.6787793040275574 [nucleus] [] 113 0.9855093359947205 1.1308892965316772 1.1736693382263184 1.0534793138504028 1.1591392755508423 1.3299893140792847 SNAPC1 1 T3-BJ 113 SNAPC1 false SNAPC1 59.120879120879124
BCOR -0.19394291937351227 0.18772666156291962 [nucleus] [] 90 0.2595973312854767 1.4962973594665527 0.4028753340244293 0.10167233645915985 0.07291433215141296 0.1021033301949501 BCOR 1 T3-BJ 90 BCOR false BCOR 67.6923076923077
NFKB1 0.27321165800094604 0.26882100105285645 [cytoplasmnucleus] [ApoptosisHSP70_and_ApoptosisIL-1_NetPath_13IL-2_NetPath_14IL-3_NetPath_15IL-4_NetPath_16IL-5_NetPath_17IL-6_NetPath_18Id_NetPath_5MAPK_signaling_pathway_KEGGMAPK_signaling_pathway_KEGGNetPath_5Oxidative_StressSmooth_muscle_contractionTGF_Beta_Signaling_PathwayTNF-alpha-NF-kB_NetPath_9] 84 0.2356676608324051 1.8313896656036377 1.6469296216964722 1.1630496978759766 0.2337946742773056 -0.06057533249258995 NFKB1 1 T3-BJ 84 NFKB1 false NFKB1 68.35164835164835
NFKB2 0.6863197684288025 0.3298943340778351 [cytoplasmnucleus] [TNF-alpha-NF-kB_NetPath_9] 87 0.4090299904346466 1.4378889799118042 1.429118037223816 1.1459929943084717 0.9060389995574951 1.0760639905929565 NFKB2 1 T3-BJ 87 NFKB2 false NFKB2 61.53846153846154
MTERFD1 1.142858624458313 0.976677656173706 [mitochondrion] [] 103 0.8882976770401001 0.858669638633728 1.0301727056503296 0.8224546909332275 0.9017806649208069 0.3848036527633667 MTERFD1 2 T6-BJ 103 MTERFD1 false MTERFD1 58.46153846153847
ZC3H8 1.3525043725967407 0.5863223075866699 [nucleus] [] 100 0.5201313495635986 0.5412953495979309 0.569355309009552 0.4882943332195282 1.169235348701477 0.7125023603439331 ZC3H8 4 T16-BJ 100 ZC3H8 false ZC3H8 68.35164835164835
IRF1 -0.02883308380842209 0.2692943215370178 [nucleus] [ApoptosisIL-7_NetPath_19] 104 0.06821266561746597 1.6353586912155151 -0.30970534682273865 -0.7479933500289917 1.0446317195892334 0.9812476634979248 IRF1 1 T3-BJ 104 IRF1 false IRF1 62.637362637362635
TP53 0.14792500436306 0.36700665950775146 [cytoplasmintracellularmitochondrionnucleus] [Androgen-Receptor_NetPath_2ApoptosisCell_Cycle-G1_to_S_control_ReactomeCell_cycle_KEGGDelta-Notch_NetPath_3G1_to_S_cell_cycle_ReactomeMAPK_signaling_pathway_KEGGMAPK_signaling_pathway_KEGGTGF-beta-Receptor_NetPath_7] 101 0.10548999905586243 0.032349999994039536 0.07541999965906143 0.07824999839067459 1.1147700548171997 0.7263299822807312 TP53 4 T16-BJ 101 TP53 false TP53 65.05494505494505
ZNF593 0.6773316860198975 0.3602093458175659 [intracellularnucleus] [] 82 0.39811766147613525 0.2998906672000885 0.379202663898468 0.3824256658554077 0.7880146503448486 1.0746726989746094 ZNF593 5 T24-BJ 82 ZNF593 false ZNF593 57.36263736263736
GTF2F2 0.6288212537765503 0.9529880285263062 [intracellularnucleus] [Androgen-Receptor_NetPath_2RNA_transcription_Reactome] 76 1.1442240476608276 1.1618809700012207 1.1480870246887207 1.0844939947128296 1.1309269666671753 1.227558970451355 GTF2F2 0 T1-BJ 76 GTF2F2 false GTF2F2 52.307692307692314
ZNF485 1.3811129331588745 0.9292076826095581 [intracellularnucleus] [] 114 0.8065366744995117 0.8570496439933777 1.4355106353759766 1.036260724067688 1.1656166315078735 0.6977686882019043 ZNF485 2 T6-BJ 114 ZNF485 false ZNF485 43.73626373626374
TNFAIP3 -0.6299839019775391 -0.13728167116641998 [cytoplasmnucleus] [TNF-alpha-NF-kB_NetPath_9] 116 2.4629123210906982 3.5764544010162354 1.977837324142456 1.6107443571090698 0.4582243263721466 1.8568493127822876 TNFAIP3 0 T1-BJ 116 TNFAIP3 false TNFAIP3 66.15384615384615
ZNF420 1.295659065246582 0.5842986702919006 [intracellularnucleus] [] 102 0.3623163402080536 0.5111023187637329 0.6892393231391907 0.5333853363990784 1.3535313606262207 0.40628233551979065 ZNF420 4 T16-BJ 102 ZNF420 false ZNF420 30.76923076923077
MYBBP1A 1.1358275413513184 0.7395859956741333 [cytoplasmintracellularnucleus] [] 83 1.1214580535888672 1.0695199966430664 1.0562289953231812 1.0628349781036377 0.8646469712257385 0.7833859920501709 MYBBP1A 0 T1-BJ 83 MYBBP1A false MYBBP1A 40.879120879120876
ZNF295 0.8183611631393433 0.8124340176582336 [intracellularnucleus] [] 110 0.7713996767997742 0.8921816945075989 0.9733866453170776 0.6836216449737549 1.2860286235809326 1.4158387184143066 ZNF295 4 T16-BJ 110 ZNF295 false ZNF295 58.901098901098905
BCL6 -0.6756085753440857 -0.2014169991016388 [intracellularnucleus] [B_Cell_Receptor_NetPath_12] 117 -0.3722803294658661 -0.4666103422641754 -0.8598863482475281 -0.5350133180618286 -0.1325843334197998 1.1531356573104858 BCL6 5 T24-BJ 117 BCL6 false BCL6 37.362637362637365
POU2F2 -0.004047332797199488 -0.08414766937494278 [nucleus] [Androgen-Receptor_NetPath_2] 92 -0.02489633299410343 0.786902666091919 1.0224716663360596 1.02019464969635 0.7359956502914429 0.8910546898841858 POU2F2 2 T6-BJ 92 POU2F2 false POU2F2 43.51648351648352
ZNF292 0.18732941150665283 0.4099763333797455 [intracellularnucleus] [] 111 0.5946066379547119 0.46920567750930786 0.6833306550979614 0.42156967520713806 1.2143737077713013 0.48669567704200745 ZNF292 4 T16-BJ 111 ZNF292 false ZNF292 36.043956043956044